DRUG-RESISTANCE

Malaria drug - resistance in Iran

Introduction: Malaria is a public health problem for approximately 2.4 billion people, 40% of the world’s population, particularly in the tropical and subtropical countries. Countries in Asia, and Latin America, the islands of the South, West, and central pacific ocean are all affected. Drug resistance is the greatest challenge in combating against malaria. Drug resistance in malaria is now w...

Drug Resistance

Fig. 15: Chloroquine sensitivity status of P. falciparum isolates in vitro (1992–2001) Monitoring Antimalarial Drug Resistance In order to understand genetic composition of the isolates in respect to commonly used antimalarials, isolates from different geographical regions were tested for their drug response either by in vitro or in vivo assay. Status of drug sensitivity in malaria parasites is...

Drug resistance.

Drug resistance and antiretroviral drug development.

As more drugs for treating HIV have become available, drug resistance profiles within antiretroviral drug classes have become increasingly important for researchers developing new drugs and for clinicians integrating new drugs into their clinical practice. In vitro passage experiments and comprehensive phenotypic susceptibility testing are used for the pre-clinical evaluation of drug resistance...